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Monoclonal Antibodies >
IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
APG01245G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) antibody - Without BSA and Azide.
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分子量 |
21kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rat
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種屬反應性 |
Human, Mouse
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克隆號 |
IL6/1270
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亞型 |
Rat / IgG1, kappa
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通用名 |
IFNB2
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基因ID |
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UniProt ID |
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功能 |
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
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總結(jié) |
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. It plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. It is involved in host defense, acute phase reactions, immune responses, and hematopoiesis.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC, IF, FC
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別名 |
Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
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圖像 |
Formalin-fixed, paraffin-embedded human Esophageal Carcinoma stained with IL-6 Monoclonal Antibody (IL6/1270). Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with IL-6 Monoclonal Antibody (IL6/1270). |
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說明書 |
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數(shù)量 |
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