IDH1 (Isocitrate Dehydrogenase) Antibody - Without BSA and Azide

APR07399G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR07399G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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IDH1 (Isocitrate Dehydrogenase) Antibody - Without BSA and Azide

品牌	Leading Biology	貨號(hào)	APR07399G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IDH1 (Isocitrate Dehydrogenase) antibody - Without BSA and Azide.
分子量	45-47kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Peroxisome
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	IDH1/1152
亞型	Mouse / IgG1, kappa
通用名	PICD
基因ID	3417
UniProt ID	O75874
總結(jié)	It recognizes a 45kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ? ?-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ? ?-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, FC
別名	Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, PICD
圖像	Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with IDH1 Monoclonal Antibody (IDH1/1152). Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with IDH1 Monoclonal Antibody (IDH1/1152).
說(shuō)明書	Product Datasheet Protocol
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IDH1 (Isocitrate Dehydrogenase) Antibody - Without BSA and Azide