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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Tenascin C (Stromal Marker For Epithelial Malignancy) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
APR11349G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Tenascin C (Stromal Marker For Epithelial Malignancy) antibody - Without BSA and Azide.
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分子量 |
210kDa and 300kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
SPM319
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亞型 |
Mouse / IgG1, kappa
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通用名 |
HXB
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基因ID |
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UniProt ID |
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功能 |
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
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總結(jié) |
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked?hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC
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別名 |
Tenascin, TN, Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, JI, Myotendinous antigen, Neuronectin, Tenascin-C, TN-C, TNC, HXB
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圖像 |
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說明書 |
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數(shù)量 |
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