CD147 / EMMPRIN / Neurothelin Antibody - Without BSA and Azide

APR07299G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07299G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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CD147 / EMMPRIN / Neurothelin Antibody - Without BSA and Azide

品牌	Leading Biology	貨號	APR07299G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD147 / EMMPRIN / Neurothelin antibody - Without BSA and Azide.
分子量	35kDa (non-reduced); 40kDa (reduced)
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250\|UniProtKB:P18572, ECO:0000269\|PubMed:17081065}
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	8D6
亞型	Mouse / IgG1
基因ID	682
UniProt ID	P35613
功能	Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
總結(jié)	This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
形式	200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P, IF, FC
別名	Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG
圖像	Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CD147 Monoclonal Antibody (8D6).
說明書	Product Datasheet Protocol
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CD147 / EMMPRIN / Neurothelin Antibody - Without BSA and Azide