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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD171 / NCAM-L1 (Axonal Marker) Antibody - Without BSA and Azide

CD171 / NCAM-L1 (Axonal Marker) Antibody - Without BSA and Azide

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG03045G 100 μg / ¥4950

CD171 / NCAM-L1 (Axonal Marker) Antibody - Without BSA and Azide

品牌

Leading Biology

貨號(hào)

APG03045G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD171 / NCAM-L1 (Axonal Marker) antibody - Without BSA and Azide.

分子量

220-240kDa

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

宿主

Mouse

種屬反應(yīng)性

Human

克隆號(hào)

SPM275

亞型

Mouse / IgG1, kappa

通用名

CAML1, MIC5

基因ID

UniProt ID

功能

Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

總結(jié)

Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

形式

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IF, FC

別名

Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD171, L1CAM, CAML1, MIC5

說(shuō)明書(shū)

數(shù)量

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