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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
APR07419G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Insulin / IRDN (beta-Cell & Insulinoma Marker) antibody - Without BSA and Azide.
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分子量 |
6kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse, Rabbit, Pig, Cow
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克隆號 |
E2-E3; same as INS04
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亞型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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總結(jié) |
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
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形式 |
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P, IF, FC
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別名 |
Insulin, Insulin B chain, Insulin A chain, INS
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圖像 |
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說明書 |
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數(shù)量 |
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