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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > ER-beta1 (Estrogen Receptor beta-1)Mouse Monoclonal Antibody [Clone ERb455]品牌 |
Leading Biology | 貨號 |
AMM04429G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ER-beta1 (Estrogen Receptor beta-1)Mouse Monoclonal antibody [Clone ERb455].
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分子量 |
53-59kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:19126643}
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat, Monkey, Pig, Sheep, Horse
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靶點 |
C-terminus fragment of recombinant human estrogen receptor beta protein
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克隆號 |
ERb455
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亞型 |
IgG2a
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通用名 |
ESTRB, NR3A2
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基因ID |
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UniProt ID |
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功能 |
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA- binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
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形式 |
0.5ml at 100ug/ml with BSA and azide
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IF, FC
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別名 |
Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta 4
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圖像 |
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說明書 |
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數(shù)量 |
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