Neurofilament (H+L) (Neuronal Marker) Antibody

APG03060G Product Datasheet Protocol

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APG03060G		7 ml / ￥4950

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Neurofilament (H+L) (Neuronal Marker) Antibody

品牌	Leading Biology	貨號	APG03060G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neurofilament (H+L) (Neuronal Marker) antibody.
分子量	200kDa & 68kDa
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Rat, Pig, Chicken
克隆號	NF421 + NFL/736
亞型	Mouse / IgG's
通用名	KIAA0845, NFH
基因ID	4744
UniProt ID	P12036
功能	Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.
總結(jié)	This MAb reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, FC
別名	Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH
圖像	Formalin-fixed, paraffin-embedded human Cerebellum stained with Neurofilament Monoclonal Antibody (NF421 + NFL/736). Formalin-fixed, paraffin-embedded Rat Cerebellum stained with Neurofilament Monoclonal Antibody (NF421 + NFL/736).
說明書	Product Datasheet Protocol
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Neurofilament (H+L) (Neuronal Marker) Antibody