PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody

APR11346G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR11346G		7 ml / ￥4950

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PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody

品牌	Leading Biology	貨號	APR11346G
產(chǎn)品分類	Monoclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PGP9.5 / UchL1 (pan-Neuronal Marker) antibody.
分子量	20-30kDa
細胞定位	Antigen Cellular Localization: Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. Note=About 30% of total UCHL1 is associated with membranes in brain
宿主	Mouse
種屬反應性	Human, Rat
克隆號	UCHL1/775
亞型	Mouse / IgG1, kappa
基因ID	7345
UniProt ID	P09936
功能	Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
總結	This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC
別名	Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, 3.4.19.12, 6.-.-.-, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, UCHL1
圖像	Formalin-fixed, paraffin-embedded Rat Testis stained with Pgp9.5 Monoclonal Antibody (UCHL1/775). Formalin-fixed, paraffin-embedded Rat Cerebellum stained with Pgp9.5 Monoclonal Antibody (UCHL1/775).
說明書	Product Datasheet Protocol
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PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody