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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody品牌 |
Leading Biology | 貨號 |
APR07367G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) antibody.
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分子量 |
94kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Rat
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Cow, Sheep, Xenopus, Horse, Guinea Pig, Dog
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克隆號 |
SPM249
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亞型 |
Rat / IgG2a, kappa
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通用名 |
GRP94, TRA1
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基因ID |
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UniProt ID |
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功能 |
Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
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總結(jié) |
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, FC
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別名 |
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1
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圖像 |
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說明書 |
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數(shù)量 |
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