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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Retinol Binding Protein-1 (RBP1) Antibody

Retinol Binding Protein-1 (RBP1) Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG01250G 7 ml / ¥4950

Retinol Binding Protein-1 (RBP1) Antibody

品牌

Leading Biology

貨號(hào)

APG01250G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Retinol Binding Protein-1 (RBP1) antibody.

分子量

21-25kDa

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

種屬反應(yīng)性

Human, Mouse, Rat, Rabbit, Monkey, Goat, Chimpanzee

克隆號(hào)

G4E4

亞型

Mouse / IgG1, kappa

基因ID

UniProt ID

功能

Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

總結(jié)

This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC, IF

別名

Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), RBP4

圖像

Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (G4E4)

說(shuō)明書(shū)

數(shù)量

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