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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > 4E-BP1 Antibody

4E-BP1 Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APG01360G 100 μl / ¥4950

4E-BP1 Antibody

品牌

Leading Biology

貨號

APG01360G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality 4E-BP1 antibody.

分子量

12580 Da

宿主

Mouse

種屬反應(yīng)性

Human

克隆號

11G12C11

亞型

IgG1

基因ID

UniProt ID

功能

Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC, E

稀釋方法

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 FC~~1:200~~400 IF~~1:200~1000.

別名

Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1

圖像

Figure 1: Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein (1).

Figure 2: Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma (A), esophagus carcinoma tissue (B) and ovary tumor tissue, showing cytoplasmic and membrane localization using 4E-BP1 mouse mAb with DAB staining.

Figure 6: Flow cytometric analysis of K562 cells using GSTP1 mouse mAb (green) and negative control (purple).

說明書

數(shù)量

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