品牌 |
Leading Biology | 貨號(hào) |
APR11927G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FGF2 antibody.
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分子量 |
30770 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane. Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
2H5G2C11
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通用名 |
FGFB
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基因ID |
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UniProt ID |
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功能 |
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
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別名 |
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2, FGF2, FGFB
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圖像 |
Figure 1: Western blot analysis using FGF2 mouse mAb against truncated FGF2 recombinant protein. Figure 2: Immunohistochemical analysis of paraffin-embedded human recturn adenocarcinoma tissue showing cytoplasmic localization using FGF2 mouse mAb with DAB staining. |
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說(shuō)明書(shū) |
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數(shù)量 |
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