品牌 |
Leading Biology |
貨號(hào) |
AMM05759G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CHRDL1 antibody.
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分子量 |
52 KDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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通用名 |
NRLN1
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基因ID |
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UniProt ID |
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功能 |
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
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總結(jié) |
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
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形式 |
Mouse monoclonal antibody purified from ascites is supplied in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, ICC
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稀釋方法 |
WB~~1:1000
ICC~~1:300
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別名 |
CHL;chordin like 1;Chordin-like protein 1;CHRDL1;CRDL1_HUMAN;dA141H5.1;neuralin 1; Neuralin-1;Neurogenesin-1;NRLN1;Ventroptin;VOPT.
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圖像 |
Western blot detection of CHRDL1 in human eye and Hela cell lysates using CHRDL1 mouse mAb (1:1000 diluted).Predicted band size: 57kDa.Observed band size: 52kDa.
Immunocytochemistry stain of Hela using CHRDL1 mouse mAb (1:300).
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說明書 |
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數(shù)量 |
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