GPR56 Antibody

APR12229G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12229G		100 μl / ￥4950

大規(guī)格詢價(jià)

3 Images

訂購信息

安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

全國授權(quán)代理商

GPR56 Antibody

品牌	Leading Biology	貨號(hào)	APR12229G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPR56 antibody.
分子量	77738 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	Recombinant Protein aa
靶點(diǎn)	This antibody is generated from a mouse immunized with a recombinant protein.
克隆號(hào)	1443CT377.65.29
亞型	IgG1,k
通用名	TM7LN4, TM7XN1
基因ID	9289
UniProt ID	Q9Y653
功能	Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis. Required for normal cortical development and regulation of neuroprogenitor cells proliferation.
總結(jié)	Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.
形式	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IF, WB, E
稀釋方法	IF~~1:25 WB~~1:2000
別名	G-protein coupled receptor 56, Protein TM7XN1, GPR56 N-terminal fragment, GPR56 NT, GPR56(N), GPR56 extracellular subunit, GPR56 subunit alpha, GPR56 C-terminal fragment, GPR56 CT, GPR56(C), GPR56 seven-transmembrane subunit, GPR56 7TM, GPR56 subunit beta, GPR56, TM7LN4, TM7XN1
圖像	Immunofluorescent analysis of 4% paraformaldehyde-fixed HeLa (human cervical epithelial adenocarcinoma cell line) cells labeling Pdx1 with APR12229G at 1/25 dilution, followed by Dylight? 488-conjugated goat anti-rabbit IgG (NK179883) secondary antibody at 1/200 dilution (green). Immunofluorescence image showing Cytoplasm staining on Hela cell line. Cytoplasmic actin is detected with Dylight? 554 Phalloidin (PD18466410) at 1/100 dilution (red). The nuclear counter stain is DAPI (blue). All lanes : Anti-GPR56 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysates Lane 2: U87-MG whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST. All lanes : Anti-GPR56 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysates Lane 2: U87-MG whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
數(shù)量

加入購物車詢價(jià)

上一產(chǎn)品：ATG4A Antibody 下一產(chǎn)品：CD20 / MS4A1 (B-Cell Marker) Antibody - Culture Supernatant

熱銷產(chǎn)品

產(chǎn)品添加成功！

購物車已有 0 件產(chǎn)品

繼續(xù)訂購查看訂購單

加入詢價(jià)單成功！

詢價(jià)單已有 0 件產(chǎn)品

繼續(xù)詢價(jià) 查看詢價(jià)單

選擇	品牌	貨號(hào)	產(chǎn)品名稱	規(guī)格	分類	研究領(lǐng)域	說明書	數(shù)量	目錄價(jià)
1	Leading Biology	APG01369G	VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價(jià)
2	Leading Biology	AMM07627G	RIN2 Antibody (monoclonal) (M01)	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價(jià)
3	Leading Biology	APR15980G	FGG Antibody	100 μl	Monoclonal Antibodies				￥5450.00	訂購詢價(jià)
4	Leading Biology	AMM05161G	GOB5 / CLCA1 Antibody (clone 1C4)	50 μg	Monoclonal Antibodies				￥5450.00	訂購詢價(jià)
5	Leading Biology	APR17667G	ORAI1 Antibody [3F6H5]	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價(jià)
6	Leading Biology	APR11118G	HIV-1 p24 Antibody [7F4] (biotin)	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價(jià)

最新加入的商品

最新加入的商品

全部產(chǎn)品分類