品牌 |
Leading Biology | 貨號 |
AMM04726G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GC antibody(Center) (Ascites).
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分子量 |
59716 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Lysosome membrane; Peripheral membrane protein; Lumenal side. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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免疫原 |
337-365 aa
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靶點 |
This GC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
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克隆號 |
660CT8.6.6.2
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亞型 |
IgM
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通用名 |
GC, GLUC
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基因ID |
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UniProt ID |
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總結(jié) |
This gene encodes a lysosomal membrane protein thatcleaves the beta-glucosidic linkage of glycosylceramide, anintermediate in glycolipid metabolism. Mutations in this gene causeGaucher disease, a lysosomal storage disease characterized by anaccumulation of glucocerebrosides. A related pseudogene isapproximately 12 kb downstream of this gene on chromosome 1.Alternative splicing results in multiple transcript variants.
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:100~1600
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別名 |
Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, GBA, GC, GLUC
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圖像 |
GC Antibody(Center) (Cat. AMM04726G) western blot analysis in MCF-7 cell line lysates (35μg/lane).This demonstrates the GC antibody detected the GC protein (arrow). |
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說明書 |
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數(shù)量 |
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