GAD2 Antibody

AMM04665G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
AMM04665G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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GAD2 Antibody

品牌	Leading Biology	貨號(hào)	AMM04665G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GAD2 antibody.
分子量	65411 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm, cytosol. Cytoplasmic vesicle. Cell junction, synapse, presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Rat
免疫原	445-473 aa
靶點(diǎn)	This GAD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from human GAD2.
克隆號(hào)	458CT17.2.4
亞型	IgG1
通用名	GAD65
基因ID	2572
UniProt ID	Q05329
功能	Catalyzes the production of GABA.
總結(jié)	This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantibody and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing results in multiple transcript variants thatencode the same protein.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:100~250
別名	Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform, GAD2, GAD65
圖像	Anti- at 1:500 dilution + human brain lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 65 kDa Blocking/Dilution buffer: 5% NFDM/TBST. GAD2 Antibody (Cat. AMM04665G) western blot analysis in mouse brain tissue lysates (35μg/lane).This demonstrates the GAD2 antibody detected the GAD2 protein (arrow). GAD2 Antibody (Cat. AMM04665G) western blot analysis in rat brain tissue lysates (35μg/lane).This demonstrates the GAD2 antibody detected the GAD2 protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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