品牌 |
Leading Biology | 貨號 |
AMM05917G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GJC2 antibody (N-term).
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分子量 |
47002 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
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宿主 |
Mouse
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種屬反應性 |
Human
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免疫原 |
32-61 aa
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靶點 |
This GJC2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GJC2.
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克隆號 |
391CT6.4.3
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亞型 |
IgM
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通用名 |
GJA12
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基因ID |
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UniProt ID |
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功能 |
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
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總結 |
GJC2 is a gap junction protein. Gap junctionproteins are members of a large family of homologous connexins andcomprise 4 transmembrane, 2 extracellular, and 3 cytoplasmicdomains. This gene plays a key role in central myelination and isinvolved in peripheral myelination in humans. Defects in this geneare the cause of autosomal recessive Pelizaeus-Merzbacher-likedisease-1.
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形式 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:100~500
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別名 |
Gap junction gamma-2 protein, Connexin-466, Cx466, Connexin-47, Cx47, Gap junction alpha-12 protein, GJC2, GJA12
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圖像 |
GJC2 Antibody (N-term) (Cat. AMM05917G ) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the GJC2 antibody detected the GJC2 protein (arrow). |
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說明書 |
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數(shù)量 |
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