ATG4D antibody (Ascites)

APG02055G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02055G		0.1 ml / ￥4950

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安諾倫（北京）生物科技有限公司

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ATG4D antibody (Ascites)

品牌	Leading Biology	貨號(hào)	APG02055G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG4D antibody (Ascites).
分子量	52922 Da
細(xì)胞定位	Antigen Cellular Localization: Cysteine protease ATG4D: Cytoplasm.
宿主	Mouse
種屬反應(yīng)性	Human
靶點(diǎn)	This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein.
克隆號(hào)	222CT15.4.1
亞型	IgG1,K
通用名	APG4D, AUTL4
基因ID	84971
UniProt ID	Q86TL0
功能	Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
總結(jié)	Autophagy is the process by which endogenous proteins anddamaged organelles are destroyed intracellularly. Autophagy ispostulated to be essential for cell homeostasis and cell remodelingduring differentiation, metamorphosis, non-apoptotic cell death,and aging. Reduced levels of autophagy have been described in somemalignant tumors, and a role for autophagy in controlling theunregulated cell growth linked to cancer has been proposed. Thisgene encodes a member of the autophagin protein family. The encodedprotein is also designated as a member of the C-54 family ofcysteine proteases.
形式	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Cysteine protease ATG4D, 3422-, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D, mitochondrial, ATG4D, APG4D, AUTL4
圖像	All lanes : Anti-ATG4D antibody at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: HL-60 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 53 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
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