品牌 |
Leading Biology | 貨號(hào) |
APR10418G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TGFB2 antibody (Ascites).
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分子量 |
47748 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.
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克隆號(hào) |
220ct16.4.3.1
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亞型 |
IgG1,K
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基因ID |
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UniProt ID |
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功能 |
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
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總結(jié) |
This gene encodes a member of the transforming growthfactor beta (TGFB) family of cytokines, which are multifunctionalpeptides that regulate proliferation, differentiation, adhesion,migration, and other functions in many cell types by transducingtheir signal through combinations of transmembrane type I and typeII receptors (TGFBR1 and TGFBR2) and their downstream effectors,the SMAD proteins. Disruption of the TGFB/SMAD pathway has beenimplicated in a variety of human cancers. The encoded protein issecreted and has suppressive effects of interleukin-2 dependentT-cell growth. Translocation t(1;7)(q41;p21) between this gene andHDAC9 is associated with Peters' anomaly, a congenital defect ofthe anterior chamber of the eye. The knockout mice lacking thisgene show perinatal mortality and a wide range of developmental,including cardiac, defects. Alternatively spliced transcriptvariants encoding different isoforms have been identified.
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形式 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:500~16000
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別名 |
Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2
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圖像 |
All lanes : Anti-TGFB2 antibody at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: HUVEC whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST. TGFB2 antibody (Cat. APR10418G) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the TGFB2 antibody detected the TGFB2 protein (arrow). |
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說明書 |
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數(shù)量 |
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