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Monoclonal Antibodies >
Cytokeratin, Multi (Epithelial Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
APR14617G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, Multi (Epithelial Marker) antibody - With BSA and Azide.
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分子量 |
Multiple KDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat, Monkey, Pig, Goat, Cow, Guinea Pig
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克隆號 |
KRT/457
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亞型 |
Mouse / IgG1
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通用名 |
K6A, KRT6D
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基因ID |
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UniProt ID |
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功能 |
Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
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總結(jié) |
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, FC
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別名 |
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, Hom s 5, KRT6A, K6A, KRT6D
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圖像 |
Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with Multi Cytokeratin Monoclonal Antibody (KRT/457). Formalin-fixed, paraffin-embedded Rat Oviduct stained with Multi Cytokeratin Monoclonal Antibody (KRT/457). |
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說明書 |
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數(shù)量 |
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