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Carbonic Anhydrase IX (Renal Cell Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM04384G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Carbonic Anhydrase IX (Renal Cell Marker) antibody - With BSA and Azide.
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分子量 |
55kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus, nucleolus. Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus membrane; Single-pass type I membrane protein. Note=Found on the surface microvilli and in the nucleus, particularly in nucleolus
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Horse
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克隆號 |
CA9/781
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亞型 |
Mouse / IgG2b, kappa
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通用名 |
G250, MN
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基因ID |
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UniProt ID |
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功能 |
Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
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總結(jié) |
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC
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別名 |
Carbonic anhydrase 9, 4.2.1.1, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1, CA9, G250, MN
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圖像 |
Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CAIX Monoclonal Antibody (CA9/781). Western Blot Analysis of HCT116 Cell Lysate using CAIX Monoclonal Antibody (CA9/781). |
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說明書 |
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數(shù)量 |
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