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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
APR14661G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) antibody - With BSA and Azide.
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分子量 |
60kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion matrix.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat, Guinea Pig, Hamster, Monkey
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靶點(diǎn) |
Recombinant human HSP60 protein
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克隆號(hào) |
LK2
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亞型 |
IgG1, kappa
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通用名 |
HSP60
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基因ID |
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UniProt ID |
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功能 |
Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
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總結(jié) |
Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-419 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp’s), more appropriately called as stress response proteins (srp’s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.
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形式 |
0.5 ml at 200ug/ml with BSA and azide
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC, IP, E
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別名 |
60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, HSPD1, HSP60
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說明書 |
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數(shù)量 |
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