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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
APR14470G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) antibody - With BSA and Azide.
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分子量 |
56.5kDa
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse
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靶點 |
Skin extract of a human Psoriasis patient
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克隆號 |
LH2
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亞型 |
IgG1
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通用名 |
KPP
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基因ID |
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UniProt ID |
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總結 |
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
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形式 |
0.5 ml at 200ug/ml with BSA and azide
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, FC, IP, E
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別名 |
Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP
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說明書 |
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數(shù)量 |
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