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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Vitamin D-binding protein Antibody

Vitamin D-binding protein Antibody

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR10729G 100 μl / ¥5450

Vitamin D-binding protein Antibody

品牌

Leading Biology

貨號

APR10729G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Vitamin D-binding protein antibody.

分子量

52964 Da

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

A synthetic peptide corresponding to residues within human VDBP was used as an immunogen.

克隆號

EP2923Y

基因ID

UniProt ID

功能

Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

總結(jié)

Vitamin-D binding protein (VDBP, DBP, Gc) is a multifunctional plasma protein that has many physiologically important functions, ranging from transporting vitamin D3 metabolites, binding and sequestering globular actin and binding fatty acids to functioning in the immune system. It is a member of a multigene family including alpha-fetoprotein and albumin. It is a serum glycoprotein that reversibly binds and transports vitamin D and its metabolites to target cells. VDBP has a triple domain modular structure with extensive disulfide bonding that is characteristic of this protein family. VDBP receptors are constitutively expressed by malignant B-cells and in a transitory form by normal B-lymphocytes undergoing mitogen-induced activation (1-4).

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC

稀釋方法

WB~~1:1000~5000 IHC~~1:100~250

別名

Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC

圖像

A. Western blot analysis on Human Plasma using anti-VDBP RabMAb (Cat. APR10729G), dilution 1:20,000.

B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Vitamin D-binding protein RabMAb (Cat. APR10729G)

說明書

數(shù)量

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