品牌 |
Leading Biology |
貨號 |
AMM08405G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Tyk2 antibody.
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分子量 |
133650 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
A synthetic peptide corresponding to residues near the C-terminus of human Tyk2 was used as an immunogen.
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克隆號 |
EP1127Y
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基因ID |
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UniProt ID |
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功能 |
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
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總結(jié) |
Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:1000~5000
IHC~~1:100~250
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別名 |
Non-receptor tyrosine-protein kinase TYK2, TYK2
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圖像 |
A. Western blot analysis on Raji cell lysate using anti-Tyk2 RabMAb (Cat. AMM08405G), dilution 1:50,000.
B. Immunohistochemical staining of paraffin-embedded human liver using anti-Tyk2 RabMAb (Cat. AMM08405G).
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說明書 |
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數(shù)量 |
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