全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR13618G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Synaptophysin antibody (C-term).
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分子量 |
33845 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
A synthetic peptide corresponding to residues in C-terminus (cytoplasmic domain) of human Synaptophysin was used as immunogen. Predicted to cross-react with bovine, based on sequence homology.
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克隆號 |
YE269
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基因ID |
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UniProt ID |
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功能 |
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
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總結(jié) |
Synaptophysin (SypI), also referred as p38 (1), constitutes approximately 7% of the total vesicle protein and is selectively associated with small synaptic vesicles (SSVs). Syp I contains four transmembrane regions and can be phosphorylated on its cytoplasmic C-terminus by both serine/threonine and tyrosine kinases (2). In addition to syp I, synaptic vesicles contain a highly homologous membrane protein named synaptoporin or synaptophysin II (Syp II) (3). While Syp I is ubiquitously expressed and present in virtually all synapses whereas Syp II is expressed at high levels only in selected neurons (4).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC, WB
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稀釋方法 |
WB~~1:1000~10000
IHC~~1:500~1000
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別名 |
Synaptophysin, Major synaptic vesicle protein p38, SYP
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圖像 |
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說明書 |
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數(shù)量 |
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