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SAA4 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMR09806G 100 μl / ¥5450

SAA4 Antibody

品牌

Leading Biology

貨號(hào)

AMR09806G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SAA4 antibody.

分子量

14747 Da

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

A synthetic peptide corresponding to residues in human SAA4 was used as an immunogen.

克隆號(hào)

EPR2926

通用名

CSAA

基因ID

UniProt ID

功能

Major acute phase reactant. Apolipoprotein of the HDL complex.

總結(jié)

Serum amyloid A (SAA) proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90% of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle (1, 2). The distribution of SAA4 is restricted to two lipoprotein subclasses; therefore, SAA4 has been suggested be a factor in lipid transfer between lipoprotein classes. SAA4 mRNA and protein expression in macrophage-derived foam cells of coronary and carotid arteries suggested a specific role of SAA4 during inflammation including atherosclerosis (3).

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC

稀釋方法

WB~~1:10000~20000 IHC~~1:50

別名

Serum amyloid A-4 protein, Constitutively expressed serum amyloid A protein, C-SAA, SAA4, CSAA

圖像

Western blot analysis on human plasma using anti-SAA4 RabMAb (Cat. AMR09806G).

Immunohistochemical analysis of paraffin-embedded normal kidney tissue using anti-SAA4 RabMAb (Cat. AMR09806G).

說(shuō)明書

數(shù)量

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