PKA, RII Antibody (C-term)

AMR09297G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMR09297G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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PKA, RII Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMR09297G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKA, RII antibody (C-term).
分子量	45518 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	A synthetic peptide corresponding to residues in the C-terminus of human cAMP-dependent protein kinase type II-alpha regulatory subunit was used as immunogen. The antibody does not cross-react with other cAMP-dependent kinase.
克隆號(hào)	Y116
通用名	PKR2, PRKAR2
基因ID	5576
UniProt ID	P13861
功能	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
總結(jié)	PKA (or cAPK) is a cyclic AMP-dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, and gene transcription (1,2). PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunits (RI and RII) have been identified, each possessing distinct cAMP binding properties and resulting in different phosphorylation states (2,3).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:500~1000 IHC~~1:100~250
別名	cAMP-dependent protein kinase type II-alpha regulatory subunit, PRKAR2A, PKR2, PRKAR2
圖像	A. Western blot analysis on K562 cell lysate using anti- PKA RII (C-term) RabMAb (Cat. AMR09297G), dilution 50,000 B. Immunohistochemical analysis of paraffin-embedded human normal breast tissue using anti-PKA RII (C-term) RabMAb (Cat. AMR09297G). C. Immunofluorescent staining of HeLa cells using anti-PKA RII (C-term) RabMAb (Cat. AMR09297G).
說(shuō)明書	Product Datasheet Protocol
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