品牌 |
Leading Biology | 貨號 |
APR17700G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality p115 antibody.
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分子量 |
107895 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
A synthetic peptide corresponding to residues near the N-terminus of human p115 was used as an immunogen.
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克隆號 |
EPR2140Y
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通用名 |
VDP
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基因ID |
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UniProt ID |
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功能 |
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
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總結(jié) |
p115 / TAP (Vesicle docking protein p115, Transcytosis-associated protein) is a general vesicular transport factor located in the Golgi complex. p115 is part of the Golgin protein family, defined by their location in the Golgi matrix and their long coiled-coil domain. p115 is thought to be essential for ER to Golgi traffic (1). Specifically, p115 is required for intercisternal transportation within the Golgi stack and required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane (2). Also, p115 has been suggested to be act as a vesicular anchor to the target membrane.
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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稀釋方法 |
WB~~1:500
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別名 |
General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
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圖像 |
A. Western blot analysis on A) HeLa, B) 293T, C) HepG2, D) Cos cell lysates using anti- p115 RabMAb (Cat. APR17700G), 1:500 dilution. |
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說明書 |
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數(shù)量 |
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