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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Neurofilament-66 Antibody

Neurofilament-66 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM06651G 100 μl / ¥5450

Neurofilament-66 Antibody

品牌

Leading Biology

貨號(hào)

AMM06651G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neurofilament-66 antibody.

分子量

55391 Da

宿主

Rabbit

種屬反應(yīng)性

Human, Rat

靶點(diǎn)

A synthetic peptide corresponding to residues in the tail domain of human NF-66 was used as immunogen.

克隆號(hào)

EP676Y

通用名

NEF5

基因ID

UniProt ID

功能

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

總結(jié)

Neurofilaments (NF) are cytoplasmic intermediate filaments (IFs) found in neurons. NF-66, also known as α-internexin, is a member of the IF family. Classified as a type IV IF, NF-66 is expressed by most neurons and has been shown to co-assemble with other NF triple proteins (light, medium and heavy NF) (1-2). In the adult brain, NF-66 is expressed at relatively low levels compared to the other NF proteins (3). NF-66 has also been shown to assemble into 10mm diameter IF in vitro.

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IF, IHC

稀釋方法

WB~~1:1000~5000 IHC~~1:250~500

別名

Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, NF-66, Neurofilament-66, Neurofilament 5, INA, NEF5

圖像

A. Western blot analysis on SHSY5Y cell lysate using anti-NF-66 RabMAb (Cat. AMM06651G).

B. Immunofluorescent staining of PC 12 cells using anti-NF-66 RabMAb (Cat. AMM06651G)

C. Positive immunohistochemical staining of paraffin-embedded human brain tissue (A.) using anti-NF-66 RabMAb.

說明書

數(shù)量

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