MIP-1 alpha Antibody (C-term)

APR17383G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR17383G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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MIP-1 alpha Antibody (C-term)

品牌	Leading Biology	貨號(hào)	APR17383G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MIP-1 alpha antibody (C-term).
分子量	10085 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted.
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	A synthetic peptide corresponding to residues in the C-terminus of human MIP 1 alpha was used as an immunogen.
克隆號(hào)	EP493Y
通用名	G0S19-1, MIP1A, SCYA3
基因ID	6348
UniProt ID	P10147
功能	Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
總結(jié)	Macrophage inflammatory protein-1 alpha (MIP-1 alpha) belongs to the intercrine beta (chemokine CC) family (1). MIP-1 alpha is involved in the acute inflammatory state, in the recruitment and activation of polymorphonuclear leukocytes and can inhibit infection of cells with human immunodeficiency virus type 1 (HIV-1) (2). MIP-1 alpha also acts as a potent growth, survival, and chemotactic factor in multiple melanoma cells. Two know isoforms of MIP-1 alpha can be found; LD78 alpha and LD78 beta (3). Depending on the isoform or its N-terminal processing, one or more of the CC chemokine receptors CCR1, CCR2, CCR3 and CCR5 can recognize MIP alpha, thus inhibiting HIV infection (4).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB
稀釋方法	WB~~1:50000
別名	C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 4641, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3
圖像	A. Western blot of anti-MIP1 alpha (C-term) RabMAb (Cat. APR17383G), dilution 1:50,000 (approximately 0.05ug/lane [0.5ug/200ul] of recombinant protein was loaded on the membrane)
說明書	Product Datasheet Protocol
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