全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM05387G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HNRPUL1 antibody.
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分子量 |
95739 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
A synthetic peptide corresponding to residues on the C-terminus of human HNRPUL1 was used as an immunogen.
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克隆號 |
EP2633Y
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通用名 |
E1BAP5, HNRPUL1
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基因ID |
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UniProt ID |
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功能 |
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand- stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
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總結(jié) |
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRPUL1) is a nuclear RNA binding protein belonging to hnRNP family.(1) HNRPUL1 interacts with adenovirus type 5 (Ad5) E1B-55 kDa, BRD7, HRMT1L1, TP53, and TAP. As a basic transcriptional regulator, HNRPUL1 represses basic transcription driven by various virus and cellular promoters. In association with BRD7, HNRPUL1 activates glucocorticoid-responsive promoter transcription in the absence of ligand-stimulation. HNRPUL1 might play an important role in nucleocytoplasmic mRNA processing and transport (2). Due to alternative splicing, five different isoform of HNRPUL1 exist.
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:1000~10000
IHC~~1:250~500
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別名 |
Heterogeneous nuclear ribonucleoprotein U-like protein 1, Adenovirus early region 1B-associated protein 5, E1B-55 kDa-associated protein 5, E1B-AP5, HNRNPUL1, E1BAP5, HNRPUL1
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圖像 |
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說明書 |
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數(shù)量 |
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