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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Gstk1 Antibody

Gstk1 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM05241G 100 μl / ¥5450

Gstk1 Antibody

品牌

Leading Biology

貨號(hào)

AMM05241G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Gstk1 antibody.

分子量

25497 Da

細(xì)胞定位

Antigen Cellular Localization: Peroxisome.

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

A synthetic peptide corresponding to residues in human Gstk1was used as an immunogen.

克隆號(hào)

EPR1939

基因ID

UniProt ID

功能

Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).

總結(jié)

Glutathione transferases (Gst) are a superfamily of enzymes that play a vital functional role in the cellular detoxification process. They catalyze the conjugation of the thiol group of glutathione to the electrophilic groups of a wide range of hydrophobic substrates, leading to an easier removal of the latter from the cells. The kappa class (Gstk) is the least studied one among various classes within the superfamily. The TRX-like domain of Gstk shares 19% sequence identity and structure similarity with the theta class Gst, suggesting that the kappa class is more closely related to the theta class enzyme within the Gst superfamily (1). Research has demonstrated that Gstk1 is expressed at relatively high levels in liver and stomach, and at moderate levels in kidney, heart, large intestine, testis, and lung. Sparse or essentially no Gstk1 protein was reported to be detected in small intestine, brain, spleen, and skeletal muscle (2).

形式

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC, IF

稀釋方法

WB~~1:500~5000 IHC~~1:250~500

別名

Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, hGSTK1, Glutathione S-transferase subunit 13, GSTK1

圖像

A.Western blot analysis on (A) fetal liver, (B) human heart, (C) 293T and (D) HeLa cell lysates using anti-Gstk1 RabMAb (Cat. AMM05241G), dilution 1:10,000.

B.Immunohistochemical analysis of parafin-embedded human liver using anti-Gstk1 RabMAb (Cat. AMM05241G).

C.Immunofluorescent staining of HeLa cells using anti-Gstk1 RabMAb (Cat. AMM05241G).

說明書

數(shù)量

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