品牌 |
Leading Biology |
貨號(hào) |
AMM04820G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Glycogen-Synthase antibody Phospho (pS641).
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分子量 |
83786 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
A synthetic phospho-peptide corresponding to residues surrounding Ser641 of human Glycogen Synthase was used as immunogen. The antibody only detects Glycogen Synthase phosphorylated on Serine 641.
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克隆號(hào) |
EP852Y
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通用名 |
GYS
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基因ID |
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UniProt ID |
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功能 |
Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
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總結(jié) |
Glycogen synthase is an enzyme of the transferase class that catalyzes the reaction of UDP-glucose and (1,4-α-D-glucosyl)n to yield UDP and (1,4-α-D-glucosyl)n+1 (1-2). This tetrameric enzyme is the rate-limiting step for glycogen synthesis (3). Glycogen concentrations are regulated by the complementary activities of glycogen phosphorylase and glycogen synthase. Glycogen synthase activity is regulated by phosphorylation of serine residues and by insulin stimulation (4). Glycogen synthase is known to have two forms; the unphosphorylated and most active form, synthase-a, and the phosphorylated glucose-6-phosphate-dependent form, synthase-b.
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:500~1000
IHC~~1:100~250
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別名 |
Glycogen [starch] synthase, muscle, GYS1, GYS
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圖像 |
A. Western blot analysis on mouse muscle lysates using anti-Phospho-Glycogen Synthase (pS641) RabMAb (Cat. AMM04820G), 1:10,000 dilution. Cells were either (A) untreated (B) treated with AP.
B. Immunohistochemical analysis of human liver using anti-Phospho-Glycogen Synthase (pS641) RabMAb (Cat. AMM04820G).
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說(shuō)明書(shū) |
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數(shù)量 |
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