GFAP Antibody (C-term)

AMM05911G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
AMM05911G		100 μl / ￥5450

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GFAP Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMM05911G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GFAP antibody (C-term).
分子量	49880 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Note=Associated with intermediate filaments
宿主	Rabbit
種屬反應(yīng)性	Human, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in the C-term of human GFAP was used as immunogen.
克隆號(hào)	EP672Y
基因ID	2670
UniProt ID	P14136
功能	GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
總結(jié)	Glial fibrillary acidic protein (GFAP) belongs to the class III of the intermediate filament (IF) proteins highly specific to astrocytes which function as nerve cells in the brain and in the central nervous system (CNS) (1-2). Two other class III IF proteins, nestin and vimentin, dominate in immature astrocytes, while GFAP is most abundant in mature astrocytes (3). GFAP is used as a marker to distinguish astrocytes form other glial cells during development. Mutations in GFAP cause Alexander disease, a rare disorder of the CNS. Most frequent mutations are located at Arginine 79 or 239 (4).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:5000~10000 IHC~~1:250~500
別名	Glial fibrillary acidic protein, GFAP, GFAP
圖像	A. Western blot analysis on Rat brain lysate using anti-GFAP (C-term) RabMAb (Cat. AMM05911G), dilution 1:2,000. B. Immunohistochemical analysis of paraffin-embedded human brain using anti-GFAP (C-term) RabMAb (Cat. AMM05911G).
說(shuō)明書(shū)	Product Datasheet Protocol
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