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Cytokeratin-7 Antibody (C-term)

APR15675G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR15675G		100 μl / ￥5450

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Cytokeratin-7 Antibody (C-term)

品牌	Leading Biology	貨號	APR15675G
產(chǎn)品分類	Monoclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytokeratin-7 antibody (C-term).
分子量	51386 Da
細胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應性	Human
靶點	A synthetic peptide corresponding to residues near the C-terminus of human CK-7 was used as an immunogen.
克隆號	EP1620Y
通用名	SCL
基因ID	3855
UniProt ID	P08729
功能	Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
總結	Cytokeratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (CK7) is expressed in a wide range of epithelial structures in humans. The expression pattern in mice is similar to the reported human distribution, with substantial expression observed in lung, bladder, mesothelium, hair follicle, and ductal structures (1). Protein expression levels of CK7 appear significantly higher in chromophobe RCC compared to oncocytoma (p < 0.001). Studies provide further evidence that CK7 and parvalbumin immunostains may be useful in differentiating oncocytoma from chromophobe RCC in problematic cases (2). Also, the pattern of immunohistochemical expression of CK 7 along with CK 20 is commonly used to assess possible primary sites of metastatic carcinomas (3).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IF
稀釋方法	WB~~1:2000~5000
別名	Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL
圖像	A. Western blot analysis on HeLa cell lysate using anti-CK-7 RabMAb (Cat. APR15675G). B. Immunofluorescent staining of HeLa cells using anti-CK-7 RabMAb (Cat. APR15675G).
說明書	Product Datasheet Protocol
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