CCR7/CKR7 Antibody (N-term)

APR15289G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR15289G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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CCR7/CKR7 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR15289G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCR7/CKR7 antibody (N-term).
分子量	42874 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in N-terminal extracellular domain of human CKR7 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members.
克隆號(hào)	Y59
通用名	CMKBR7, EBI1, EVI1
基因ID	1236
UniProt ID	P32248
功能	Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
總結(jié)	CKR7, or C-C chemokine receptor type 7, is a G protein-coupled, seven-transmembrane domain receptor protein. Originally identified as the EBV-induced gene-1 (1), CKR7 was later found to be the receptor for the chemokines CCL21 (SLC, 6Ckine, Exodus-2) (3) and CCL19 (MIP-3 beta, Exodus-3, ELC) (4). CCR7 is expressed in lymphoid tissues and activated B and T lymphocytes (2). It is up-regulated in B cells infected with Epstein-Barr virus and T cells infected with herpesvirus 6 or 7 (4).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:10000 IHC~~1:250
別名	C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1
圖像	A. Western blot analysis on (left) K562 and (right) Daudi cell lysates using anti-CKR7/CCR7 (N-term) RabMAb (Cat. APR15289G), dilution 1:5,000. B. Immunohistochemical analysis of paraffin-embedded human spleen using anti-CKR7/CCR7 (N-term) RabMAb (Cat. APR15289G). C. Immunofluorescent staining of HeLa cells using anti-CKR7/CCR7 (N-term) RabMAb (Cat. APR15289G).
說明書	Product Datasheet Protocol
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