C/EBP alpha Antibody (N-term)

APG02302G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02302G		100 μl / ￥5450

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C/EBP alpha Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APG02302G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality C/EBP alpha antibody (N-term).
分子量	37561 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應(yīng)性	Human, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in the N-term of human C/EBP alpha was used as immunogen. This antibody recognizes both the 42kDa and the 30kDa isoforms.
克隆號(hào)	EP708Y
基因ID	1050
UniProt ID	P49715
功能	C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.
總結(jié)	CCAAT/enhancer-binding proteins (C/EBP) consist of a family of transcription factors that play an important role in regulating the balance between cell growth & differentiation. The various isoforms of C/EBP (α,β,γ,δ,ε, ζ ) exhibit similar DNA-binding specificities and contain a leucine zipper dimerization domain (1). C/EBP alpha (2) can form heterodimers with related protein C/EBP beta and gamma. C/EBP alpha directly interacts with CDK2and CDK4 and arrests cell proliferation by inhibiting these kinases (3). C/EBP alpha has been shown to bind to the promoter and modulate the expression of leptin, a protein that plays an important role in body weight homeostasis (4). C/EBP alpha also has prominent antimitotic activity and may play a role of a tumor suppressor (5).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF
稀釋方法	WB~~1:500
別名	CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBPA
圖像	A. Western blot analysis on U937 + LPS cell lysate using anti-C/EBP alpha (N-term) RabMAb (Cat. APG02302G), dilution 1:50,000. B. Immunofluorescent staining of HeLa cells using anti-C/EBP alpha (N-term) RabMAb (Cat. APG02302G).
說(shuō)明書	Product Datasheet Protocol
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