品牌 |
Leading Biology |
貨號(hào) |
AMM05624G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BM88 antibody.
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分子量 |
14954 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type IV membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
A synthetic peptide corresponding to residues in human BM88 was used as an immunogen.
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克隆號(hào) |
EPR3738
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通用名 |
BM88
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基因ID |
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UniProt ID |
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功能 |
Involved in neuroblastoma cell differentiation.
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總結(jié) |
BM88 is a neuron-specific protein widely distributed in the nervous system and implicated in cell cycle exit and differentiation of neuronal precursors (1, 2). It is an integral membrane protein, which appears early during brain development and remains at high levels at the mature state (1). It is expressed in terminally differentiated neurons and also in neuronal progenitors, in lower levels. BM88 expression shows a tight correlation with the progression of progenitor cells towards neuronal differentiation (2). BM88 is crucial for the transition from neuroblasts to mature neurons when reaching high levels (3).
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形式 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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稀釋方法 |
WB~~1:1000~10000
IHC~~1:100~250
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別名 |
Cell cycle exit and neuronal differentiation protein 1, BM88 antigen, CEND1, BM88
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圖像 |
Western blot analysis on (A) fetal brain, (B) Neuro-2a and (C) SH-SY5Ycell lysates using anti-BM88 RabMAb (Cat. AMM05624G).
Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-BM88 RabMAb (Cat. AMM05624G).
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說明書 |
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數(shù)量 |
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