ACADM Antibody

APG01435G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01435G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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ACADM Antibody

品牌	Leading Biology	貨號(hào)	APG01435G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACADM antibody.
分子量	46588 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion matrix.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide corresponding to residues in human ACADM was used as an immunogen.
克隆號(hào)	EPR3708
基因ID	34
UniProt ID	P11310
功能	This enzyme is specific for acyl chain lengths of 4 to 16.
總結(jié)	Medium-chain specific acyl-CoA dehydrogenase (ACADM) is a homotetramer enzyme of the mitochondrial flavoenzyme family that catalyzes the initial reaction in medium chain fatty acid beta-oxidation (1, 2). ACADM is specific for acyl chain lengths of 4 to 16 (3). It utilizes the electron transfer flavoprotein (ETF) as an electron acceptor that transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (3). Defects in the ACADM gene cause medium-chain acyl-CoA dehydrogenase deficiency (MCADD), a metabolic disorder characterized by fasting hypoglycemia (3). Mutation analysis can diagnose MCADD, which is currently screened in newborns, since its monogene may be modified by genetic variations (4).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:1000~10000 IHC~~1:100~250
別名	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD, ACADM
圖像	Western blot analysis on (A) human heart, (B) fetal liver, (C) HeLa, (D) HepG2, and (E) K562 cell lysates using anti-ACADM RabMAb (Cat. APG01435G). Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ACADM RabMAb (Cat. APG01435G). Immunofluorescent staining of HeLa cells using anti-ACADM RabMAb (Cat. APG01435G).
說(shuō)明書	Product Datasheet Protocol
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