Aldh7A1 Antibody

APR14912G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR14912G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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Aldh7A1 Antibody

品牌	Leading Biology	貨號(hào)	APR14912G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Aldh7A1 antibody.
分子量	58487 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion. Nucleus
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	A synthetic peptide corresponding to residues near the C-terminus of human Aldh7a1 was used as an immunogen.
克隆號(hào)	EP1935Y
通用名	ATQ1
基因ID	501
UniProt ID	P49419
功能	Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.
總結(jié)	Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3).
形式	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC
稀釋方法	WB~~1:1000 IHC~~1:100~250
別名	Alpha-aminoadipic semialdehyde dehydrogenase, Alpha-AASA dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Antiquitin-1, Betaine aldehyde dehydrogenase, Delta1-piperideine-6-carboxylate dehydrogenase, P6c dehydrogenase, ALDH7A1, ATQ1
圖像	A.Western blot analysis on human liver lysate using anti-Aldh7a1 Rabbit Monoclonal (Cat. APR14912G). B. Immunohistochemical analysis of paraffin-embedded human liver using anti-Aldh7a1 RabMAb (Cat. APR14912G).
說明書	Product Datasheet Protocol
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