Functional TRAIL-R2 (human) Antibody, mAb(preservative free)

AMP00002G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMP00002G		100 μg / ￥5450

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

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Functional TRAIL-R2 (human) Antibody, mAb(preservative free)

品牌	Leading Biology	貨號(hào)	AMP00002G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Functional TRAIL-R2 (human) Antibody, mAb(preservative free).
分子量	47878 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Purified From Concentrated Hybridoma Tissue Culture Supernatant.
種屬反應(yīng)性	Human
靶點(diǎn)	Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
克隆號(hào)	HS201
亞型	Mouse IgG1
通用名	DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
基因ID	8795
UniProt ID	O14763
功能	Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis.
總結(jié)	TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
形式	Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P, FC, ICC, IP
圖像	Immunohistochemical staining of TRAIL-R2 using anti-TRAIL-R2 (human), mAb (HS201) in formalin-fixed and paraffin-embedded (FFPE) human liver tissue (15 μg/ml).
說明書	Product Datasheet Protocol
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Functional TRAIL-R2 (human) Antibody, mAb(preservative free)