全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM02010G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMURF1 Antibody (clone 1D7).
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分子量 |
86kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse
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靶點 |
Human SMURF1
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克隆號 |
1D7
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通用名 |
KIAA1625
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基因ID |
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UniProt ID |
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功能 |
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.
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總結(jié) |
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E, IP
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稀釋方法 |
IF (10 μg/ml), IHC-P (5 μg/ml),
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圖像 |
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說明書 |
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數(shù)量 |
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