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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Vitamin D Receptor / VDR Antibody (clone 2F4)品牌 |
Leading Biology | 貨號 |
AMM01929G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Vitamin D Receptor / VDR Antibody (clone 2F4).
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分子量 |
48kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
2F4
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通用名 |
NR1I1
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基因ID |
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UniProt ID |
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功能 |
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
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總結(jié) |
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P, E
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稀釋方法 |
IHC-P (5 μg/ml)
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圖像 |
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說明書 |
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數(shù)量 |
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