品牌 |
Leading Biology |
貨號 |
AMM02596G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Lamin A/C Antibody.
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分子量 |
64, 74 KDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Bovine, Human, Mouse, Rat
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靶點(diǎn) |
Recombinant full length human lamin C expressed in and purified from E. Coli.
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克隆號 |
4C4
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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總結(jié) |
Lamins A and C are nuclear structural proteins that are part of the intermediate filament family and coded for by the same gene (LMNA). Lamins A and C are nearly identical except for their carboxy termini (McKeon et al., 1986). Mutations in the gene encoding lamins A/C have been shown to cause a variety of diseases including autosomal dominant Emery-Dreifuss muscular dystrophy (Bonne et al., 1995), autosomal dominant limb-girdle muscular dystrophy (Muchir et al., 2000) and Charcot-Marie-Tooth disorder type 2 (De Sandre-Giavonnoli et al., 2002).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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稀釋方法 |
WB~~ 1:5000
IF~~ 1:1000
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圖像 |
Western blot of HeLa lysate showing specific immunolabeling of the ~ 64k and 74k lamin A/C proteins.
Immunofluorescence of HeLa cells showing strong nuclear lamina staining of lamin A/C in red andvimentin in green.
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說明書 |
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數(shù)量 |
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