品牌 |
Leading Biology | 貨號 |
AMM02592G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Synaptobrevin (VAMP) Antibody.
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分子量 |
16 KDa
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宿主 |
Mouse
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種屬反應性 |
Bovine, Human, Hamster, Mouse, Pig, Rat, Rabbit
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靶點 |
Synaptic immunoprecipitate (crude) from human brain.
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克隆號 |
SP10
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亞型 |
IgM
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基因ID |
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UniProt ID |
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總結 |
Synaptobrevin (aka VAMP) is an integral membrane protein ofsynaptic vesicles that plays a major role in the formation of larger SNARE complexes, alongwith SNAP-25 and syntaxin. Synaptobrevin hasbeen shown to be essential for two fastsynapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter releaseand fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004).Decreased levels of synaptobrevin in human hippocampus and cortex have been correlatedwith cognitive defects in Alzheimer’s disease (Sze et al., 2000)
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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稀釋方法 |
WB~~ 1:1000
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圖像 |
Western blot of rat brain lysate showing specific immunolabelingof the ~ 16k synaptobrevin protein. |
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說明書 |
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數(shù)量 |
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