品牌 |
Leading Biology |
貨號(hào) |
AMM00010G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Proteinase Inhibitor 6 (PI-6) Antibody (Clone 3A).
|
分子量 |
42622 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm
|
宿主 |
Mouse
|
種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
PI6
|
克隆號(hào) |
3A
|
亞型 |
Mouse IgG2b/k
|
通用名 |
PI6, PTI
|
基因ID |
|
UniProt ID |
|
功能 |
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
|
總結(jié) |
Proteinase inhibitor 6 (PI-6) is a 42 kDa cytoplasmic protein belonging to the serine proteinase inhibitor (serpin) super family and the ovalbumin-serpin super family. Sequence similarity s μggests that PI-6 most resembles the ovalbumin serpins . Highest levels of PI-6 are found in skeletal muscle. PI-6 is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas.
|
形式 |
Liquid
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
IF, FC, IP
|
說明書 |
|
數(shù)量 |
|