品牌 |
Leading Biology | 貨號 |
AMM02993G |
產品分類 |
Monoclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MLANA Antibody.
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分子量 |
13.2kDa
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
2F3B7
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亞型 |
IgG1
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通用名 |
MART1
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基因ID |
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UniProt ID |
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功能 |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
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總結 |
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. ; ; ;
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
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圖像 |
Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Figure 1: Western blot analysis using MLANA mAb against human MLANA (AA: 48-118) recombinant protein. (Expected MW is 33.9 kDa) Figure 2: Western blot analysis using MLANA mAb against HEK293 (1) and MLANA (AA: 48-118)-hIgGFc transfected HEK293 (2) cell lysate. |
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說明書 |
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數量 |
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