全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM02969G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMCP Antibody.
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分子量 |
12.8kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Note=Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
5C10A2
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亞型 |
IgG2b
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通用名 |
MCS, MCSP
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基因ID |
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UniProt ID |
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功能 |
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity).
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總結(jié) |
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. ;
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
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圖像 |
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說明書 |
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數(shù)量 |
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